INTRODUCTION
We secured multiple pseudoindoxyl reference samples, partnered with a University lab that were experts in pseudoindoxyl testing, and worked to build both a calibration set and internal reference standards.
We have now tested hundreds of samples for pseudoindoxyl as a free add-on to our standard Kratom testing. We’ve referenced those externally against known references at labs we trust, and have built a calibration set from 0.1% up to 100% purity.
We are already experts with 7OH testing, and have tested virtually every major brand currently on the market, either as clients, or to build out our portfolio of 7OH products. We pride ourselves on consistency and accuracy, and the only way to do that is to continually test ourselves against reference standards and other labs.
Shockingly, we’ve found very large variations in many of the most popular testing labs. We know of one that returns results 7-10% higher than a referenced standard. We also have seen labs under-reporting potency. Our guess is that it’s because they don’t specialize in both Kratom and Kava like we do. I can’t remember that last day when we didn’t have a Kratom sample set in for testing. In fact, I can’t remember the last day we had less than 5 clients at a time.
We test Kava and Kratom every single day. We run calibration samples alongside every single sample we run. And, if we get an odd result, we always assume first that we are wrong. That automatically triggers a re-prep and a re-test, to ensure that the same result a second time.
PSEUDOINDOXYL STABILITY
We have been testing pseudoindoxyl for over a decade now. We simply didn’t have a reference sample for testing until early 2024, when our favorite chemical house finally offered a pseudo reference sample for sale. Because of that, and because we keep client samples for 3-5 years, we were able to go back and not only test pseudo in previous samples, but 7OH and MIT as well. What we found was extremely interesting; 7OH breaks down over time faster than pseudo does.
Now, these aren’t official stability tests; they’re just our observations. But the evidence speaks for itself. We’re still trying to figure out how the industry is going to use pseudo in products since it’s a by-product of 7OH conversion. That makes it extremely expensive, and in many ways, a pointless exercise.
Liquids are still a challenge for both 7OH and pseudo though, with pH being one of the key factors in maintaining stability of these 2 alkaoids over time.